None listed
Conditions
Brief summary
This study examines the effect of weight cycling on iron status, inflammation and immune function. The objective is to measure iron levels, inflammation and the immune systems of young women and then investigate how weight cycling can affect these factors. This research study is part of larger trial that is comparing the effectiveness of a red meat based, low fat diet and a white meat based, low fat diet on weight loss, immune function, blood fats, glucose, insulin and iron levels.
Interventions
This is a cross-sectional study that observed weight cycling history, iron and inflammatory markers at one time point. Anthropometric data including height, weight, BMI, waist circumference, as well as body composition data including percent body fat, absolute fat mass and lean mass (using both bio-electrical impedance and dual x-ray absorptiometry measurement techniques) were collected. Self-reported history of weight cycling, weight loss and attempts at weight loss in the past five years was recorded. Participants were also required to undergo one blood test to measure concentration of iron, inflammatory and immune markers.
Sponsors
Eligibility
Inclusion criteria
Body mass index equal to or above 27.5 kg/m2
Exclusion criteria
Self-report of significant medical conditions (e.g. diabetes mellitus, disorders of the liver (including hemochromatosis) and kidney, autoimmune or metabolic diseases and malignancy) or use of medications that may influence weight, iron or inflammatory status; pregnancy or lactation; vegetarianism; smoking; and previous bariatric surgery. Volunteers reporting iron supplementation or blood donation within three months prior to recruitment were asked to participate only following a three month washout period