None listed
Conditions
Brief summary
Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. In addition to generating high healthcare costs, COPD imposes a significant burden in terms of disability and impaired quality of life. Unlike many leading causes of death and disability, COPD is projected to increase in much of the world as smoking frequencies rise and the population ages. The use of home oxygen for hypoxic COPD patients has increased since studies have shown improved survival. Home oxygen however is cold and dry and may be uncomfortable and lead to thickened secretions. This study aims to assess the feasibility and short term physiological respiratory changes caused by using an alternative device AIRVO (high flows of warmed and humidified air enriched oxygen ) versus the currently used home oxygen (low flow oxygen therapy).
Interventions
In a randomised crossover study patients will be studied on their usual home oxygen (Control) and on AIRVO (Treatment).
Treatment
* Patient receives usual home oxygen while equipment is set up (20 minutes)
* Baseline observations on usual home oxygen will be recorded (20 minutes)
* Participant receives treatment/control (20 minutes)
* Washout period on usual home oxygen (20 minutes)
* Participant receives treatment/control (20 minutes)
* Recovery period on usual home oxygen (20 minutes)
Note
In a randomised crossover study patients will be studied on their usual home oxygen (Control) and on AIRVO (Treatment). Treatment * Patient receives usual home oxygen while equipment is set up (20 minutes) * Baseline observations on usual home oxygen will be recorded (20 minutes) * Participant receives treatment/control (20 minutes) * Washout period on usual home oxygen (20 minutes) * Participant receives treatment/control (20 minutes) * Recovery period on usual home oxygen (20 minutes) Note: *Usual home oxygen - patient receives the usual oxygen flow rate received at home via their own cannulae *AIRVO - oxygen flow into the Airvo system is titrated to give an oxygen saturation the same as the patient receives on their own cannulae along with a flow of 30L/min
Sponsors
Critical Care Research Group, The Prince Charles Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator)
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Male COPD patients requiring home oxygen * Formal spirometry data less than one year old
Exclusion criteria
* Co-morbidities that may effect respiratory function or physiological measurements * Active respiratory infection on day of study * Frequent pursed-lip breathing * Anxiousness about breathing with a system different to their current one
Outcome results
None listed