Models of care for Acute Non-invasive Ventilation- Comparison of three tertiary Centres.

Three Acute non-invasive ventilation services based in metropolitan Melbourne in the hospital ward (The Alfred Hospital), high dependency unit (Royal Melbourne Hospital) and intensive care unit (Boxhill Hospital) deliver equivalent patient outcomes and are equally cost effective.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12613000011785

Acronym

ACT3

Enrollment

Registered

2013-01-07

Start date

2011-03-01

Completion date

2011-03-01

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim is to compare three different acute non invasive ventilation services in three tertiary centres in Melbourne. All data has been collected on a password protected microsoft access database. Only a select few have the password. This study is a prospective observational study all patients received their usual care and data is de identified.

Interventions

Prospective observational non-inferiority study comparing the acute non-invasive ventilation services (NIV) at The Alfred, Royal Melbourne and Boxhill Hospital. All patients received their usual care. Usual care included all medications required to treat an exacerbation of COPD including controlled oxygen, steriods (either inhaled/ oral or Intra venously), current inhaled respiratory medications and antibiotics if required. Inclusion criteria- Adult patients admitted with Acute exacerbation of chronic pulmonary disease (AECOPD) by standard criteria (GOLD) complicated by acute respiratory acidosis. Exclusion criteria- Chronic obstructive pulmonary disease (COPD) patients treated with non-invasive ventilation for weaning post mechanical ventilation. The study duration was 14 months.

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Adult patients admitted with AECOPD by standard criteria (GOLD) complicated by acute respiratory acidosis (PH <7.35, PaC02>45mmHg) managed with BIPAP. Includes patients who are trialled on NIV but intolerant of treatment.

Exclusion criteria

COPD patients treated with BIPAP for weaning post mechanical ventilation.

Outcome results