None listed
Conditions
Brief summary
The aim of the study is to evaluate brain perfusion on Tc-99m ECD SPECT/CT, cognition function test and questionnaires in OSA patients before and after treatment.
Interventions
There are two interventions (CPAP and surgery).
CPAP: Brad of ResMed-- S8 autoset Spirit in automatic positive airway pressure model. The participants put on the facial mask when sleeping, open the power of machine and the machine will start to work and automatically give the postitive pressure. Duration: 4 to 8 hours a day for 3 months
Surgery: Uvulopalatopharyngoplasty, occur once. Approximate duration of uvulopalatopharyngoplasty: 1 hour
All participants undergo only one intervention. Either
There are two interventions (CPAP and surgery). CPAP: Brad of ResMed-- S8 autoset Spirit in automatic positive airway pressure model. The participants put on the facial mask when sleeping, open the power of machine and the machine will start to work and automatically give the postitive pressure. Duration: 4 to 8 hours a day for 3 months Surgery: Uvulopalatopharyngoplasty, occur once. Approximate duration of uvulopalatopharyngoplasty: 1 hour All participants undergo only one intervention. Either CPAP or surgery treatment will be chosen by each participant.
Sponsors
Show Chwan Memorial Hospital
Study design
Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Diagnosis
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
moderate and severe degree obstructive sleep apnea patients age: 20~60 years old
Exclusion criteria
Patients with symptoms of present of other sleep disorder, history of receiving medical intervention for sleep-related breathing disorder, cognition deterioration, hypertension, cancer, use of psychoactive medication, history of head injury with conscious loss and structural brain abnormalities
Outcome results
None listed