Investigating the effectiveness of Elderberry capsules in the prevention of upper respiratory symptoms associated with long distance travel.

Randomised, double-blind, placebo-controlled trial of Elderberry supplementation preventing upper respiratory symptoms in air travellers.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612001301853

Enrollment

280

Registered

2012-12-17

Start date

2013-04-26

Completion date

2014-12-10

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will investigate the effectiveness of Elderberry lozenges in the prevention of upper respiratory symptoms associated with long distance travel.

Interventions

Elderberry capsules (active) are 300mg of standardised Elderberry membrane filtered extract powder (22% polyphenols, 15% anthocyanins) and 150mg of rice flour. Participants will take 2 capsules per 24 hour period for 10 days prior to travel, 3 capsules per 24 hour during travel and a further 4 days at their destination. Trial participation lasts 16 days including the first 4 or 5 days on arriving at their destinations. Travel duration will differ between participants and should not exceed 72 hou

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1) travelling a minimum of 7 hours flight 2) travelling via economy class 3) planning a minimum stay of 4 days at destination

Exclusion criteria

1) Diagnosed respiratory disease 2) Lactation or pregnancy 3) Pollen/plant allergy 4) Serious inflammatory or immunological conditions

Outcome results