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Does carbon dioxide insufflation during colonoscopy minimise post colonoscopy pain?: A randomised controlled trial

Does carbon dioxide insufflation for a patient during colonoscopy minimise their post colonoscopy pain compared to air.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612001297819
Enrollment
240
Registered
2012-12-17
Start date
2008-07-01
Completion date
2009-01-30
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of the study is to determine that carbon dioxide (CO2) , instead of air insufflated during colonoscopy reduces pain experienced by patients post colonoscopy. the Hypothesis: Those receiving carbon dioxide (CO2) insufflation during colonscopy will experience less post colonoscopy pain than those receiving air insufflation.

Interventions

Carbon dioxide (a medicinal gas) was drawn from a CO2 tank and delivery system to a receptacle and then passed intermitently through the endoscope during the colonoscopy at the control of the endoscopist pressing a button on the hand piece of the endoscope. The intention of gas is to insufflate the colon during colonoscopy.

Sponsors

MidCentral District Health Board
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
16 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

Patients on the waiting list for elective colonoscopy. These will be new patients with symptoms and also patients for surveillance colonoscopy (for reasons of past history of; colon cancer, adenomas, strong family history of bowel cancer and inflammatory bowel disease)

Exclusion criteria

Age under 16 and over 90 Inability to understand participant information Patients with severe chronic obstructive pulmonary disease (COPD) Refusal to participate

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026