Traditional Chinese Medicine (TCM) Constitution in patients with obstructive sleep apnea syndrome (OSAS) treated with continuous positive airway pressure (CPAP).

Among patients with obstructive sleep apnea syndrome, is the treatment with continuous positive airway pressure improving constitution in Traditional Chinese Medicine?

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612001285842

Enrollment

Registered

2012-12-12

Start date

2011-04-18

Completion date

2013-04-30

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Obstructive sleep apnea syndrome (OSAS) is composed of sleeping apnea and hypopnea. It also accompanied with fatigue, daytime sleepiness and poor concentration and memory in such patients. The standard treatment for it is usage of continuous positive airway pressure during sleeping. In this study, we want to know condition of Traditional Chinese Medicine (TCM) constitution in patients with OSAS, and to see if treatment of CPAP improves patients' TCM constitution.

Interventions

nasal continuous positive airway pressure (nCPAP), participant will wear it during sleeping at least 4 hours per night and lasted for twelve weeks. Initial pressure of CPAP is set between 4-20 cm H2O, and will be adjusted in a 4-week interval according to participant's response.

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

patients with obstructive sleep apnea syndrome which is diagnosed by polysomngraphy

Exclusion criteria

1. patients who refuse to receive treatment of CPAP 2. patients who have some situation that CPAP is not the first choice and other treatment is suggested (eg. surgical intervention for tonsil enlargement). 3. patients who has underlying diseases of chronic obstructive pulmonary disease, myocardial infarction, heart failure, stroke, liver diseases, kidney diseases, neurogic and muscular disorders, metabolic diseases, immunosuppressed diseases, and malignancy

Outcome results