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Australian Cerebral Palsy Child: a prospective cohort study of motor development and brain structure in young children with cerebral palsy.

Australian Cerebral Palsy Child- a prospective cohort study of motor development and brain structure in young children, with cerebral palsy born in Queensland in 2006, 2007, 2008 and 2009.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12612001269820
Acronym
CPchild
Enrollment
240
Registered
2012-12-04
Start date
2005-08-03
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This prospective, population based longitudinal study of children, with cerebral palsy, aged 18 months to 5 years will track early motor development and will utilise magnetic resonance imaging to determine the anatomical pattern and likely aetiology and timing of the brain lesion. This will help predict the likely need for, type and timing of interventions(spasticity management, rehabilitation, orthopaedic surgery) and their associated costs, this study will enable more informed resource planning for cerebral palsy in young children for the future.

Interventions

Longitudinal measurement of Gross Motor Function (GMFM 66), Gross motor function classification, motor type, distribution(bilateral, unilateral), brain structure (location, extent, presumed timing of lesion), classification of comorbidities(epilepsy,vision,hearing,health status), musculoskeletal development, participation and relationship between motor prognosis and resource use at 18 months, 2 years, 30 months, 3 years, 4 years and 5 years corrected age.

Sponsors

Professor Roslyn Boyd
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Months to 5 Years
Healthy volunteers
No

Inclusion criteria

All children diagnosed with cerebral palsy, born in Victoria between 1 January 2004 and 31 December 2005; and in Queensland between 1 January 2006 and 31 December 2009. We define cerebral palsy a a group of permanent disorders of movement and posture that attributed to non-progressive disturbances that occurred in the developing foetal or infant brain. The characteristic signs are spasticity, movement disorders, muscle weakness, ataxia and rigidity.

Exclusion criteria

Children with a progressive or neurodegenerative lesion will be excluded from the study.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026