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Exercise Physiologists in Renal Dialysis

The effect of a lower body resistance exercise program, administered by accredited exercise physiologists, on the physical function of adults receiving 3 weekly haemodialysis

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612001223820
Acronym
ExPiReD
Enrollment
177
Registered
2012-11-19
Start date
2013-05-01
Completion date
2014-01-01
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will measure the direct impact of an exercise program on the health outcomes of people with chronic kidney disease on dialysis. The health outcomes that will be measured include: physical function, quality of life, uptake of community exercise programs, self-reported falls, and biochemical markers. This work is significant given the effects of end stage kidney disease on musculoskeletal health in this group. There is a current absence of exercise programs in haemodialysis clinics globally, leading to a decline in dialysis patients’ physical function and increased costs to health services. Study Hypothesis: Accredited exercise physiologists providing a resistance exercise program will improve the physical function of people with chronic kidney disease receiving haemodialysis.

Interventions

Resistance Exercises: Leg abduction, plantar flexion, dorsi flexion, straight-leg/bent-knee raise, knee extension and knee flexion. All resistance exercises will be done in a seated position while still receiving dialysis treatment. The exercises will be done during the first hour of dialysis treatment. When participants are able to perform two sets of 15-20 repetitions for each exercise, the resistance exercises will be made progressively harder using different colour-graded elastic bands and t

Resistance Exercises: Leg abduction, plantar flexion, dorsi flexion, straight-leg/bent-knee raise, knee extension and knee flexion. All resistance exercises will be done in a seated position while still receiving dialysis treatment. The exercises will be done during the first hour of dialysis treatment. When participants are able to perform two sets of 15-20 repetitions for each exercise, the resistance exercises will be made progressively harder using different colour-graded elastic bands and tubings. Participants will also be encouraged to perform each exercise (lifting phase - concentric contraction) as rapidly as possible to optimise movement speed and muscle power. The sessions will last between 30 and 60 minutes and performed 3 times a week to coincide with patients' existing dialysis treatment schedule. The stepwedged design will provide the intervention for 3, 6 or 9 months depending on the randomly allocated group. This will mean that all groups will receive at least 3 months of the intrevention.

Sponsors

Associate Professor Paul Bennett
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Other
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

People with end stage renal disease Receiving haemodialysis greater than three months Able to understand spoken English

Exclusion criteria

Previous lower limb amputation Hospitalised in the month prior to study commencement

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 10, 2026