None listed
Conditions
Brief summary
This is a comperative study of two surgical interventions in infertile men with varicocele. Both interventions are widely accepted, but only retrospective studies proved their equivalence. In our opinion microsurgical intervention is superior both in terms of safety and efficacy. The only good comparison may be done in a prospective manner.
Interventions
laparoscopic varicocelectomy (standard urologic procedure in infertile patients with varicocele). Transperitoneal (3 trocars 10 mm; 10 mm; 5 mm) approach with ligation of spermatic left vein.
Participants will be observed for a follow-up period of 12 months after completion of surgery. The laparoscopic varicocelectomy surgical procedure takes approximately 30 minutes per participant
Sponsors
Piotr Bryniarski
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
a. Palpable varicocele (no subclinical) one or both sides b. Infertility (primary and secondary) over 12 months c. Oligozoospermia (<15 mln/ml) or astenozoospermia (<32%) or teratozoospermia (<4%) in semen analysis d. Male factor (healthy women) e. No other cause of infertility in men f. Normal TSH
Exclusion criteria
a. Azoospermia b. Recurrent varicocele c. Undescended testis d. Mumps e. Secondary hypogonadism f. Hyperprolactynemia g. Testosterone/antiestrogen therapy h. Age over 40 i. History of testis cancer
Outcome results
None listed