Does Vitamin D supplementation in pregnancy improve maternal glucose metabolism or prevent gestational diabetes?

Effect of high-dose versus low-dose vitamin D supplementation in pregnancy on maternal glucose metabolism and the risk of gestational diabetes.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612001145897

Enrollment

200

Registered

2012-10-30

Start date

2010-02-10

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will determine whether taking additional Vitamin D supplementation in pregnancy, above that contained in conventional pregnancy vitamin tablets, improves a woman's glucose metabolism and prevents the development of gestational diabetes, a common complication of pregnancy in Australia.

Interventions

Pregnant women will be randomly allocated to take high-dose vitamin D supplementation (5000IU/day) or standard dose pregnancy vitamin supplementation (400 IU vitamin D daily), administered as an oral capsule, from the time of the first antenatal clinic visit (around 12 weeks gestation) until delivery.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Pregnancy, less than 20 weeks gestation at recruitment.

Exclusion criteria

Known diabetes Calcium metabolic disorder Multiple pregnancy

Outcome results