None listed
Conditions
Brief summary
Effective management of Type 1 diabetes requires matching of insulin to dietary carbohydrate in order to achieve tight glycaemic control without excessive hyper or hypoglycaemia. This can be challenging, particularly when carbohydrate intake is high or variable. Current management focuses on providing patients with skills to estimate amounts of carbohydrate and match insulin to this. An alternative approach is to reduce levels of dietary carbohydrate. This is a randomised controlled trial of a low carbohydrate diet compared with the current standard carbohydrate counting treatment in 16 adults with Type 1 diabetes. Outcomes being measured include glucose excursion over 24 hours, glycaemic control, renal function and quality of life.
Interventions
A low carbohydrate diet (50-75g of carbohydrate total per day patients choice of level within this range) over 12 weeks. Participants will be given information on carbohydrate amounts in foods and guidance on selecting up to 75g per day, with unlimited protein and free vegetables. Added fats will be encouraged to be limited and good choices in line with cardiocascular health advice. 8 participants will be randomised to this arm and will attend 4 group sessions to learn about the diet and matchin
A low carbohydrate diet (50-75g of carbohydrate total per day patients choice of level within this range) over 12 weeks. Participants will be given information on carbohydrate amounts in foods and guidance on selecting up to 75g per day, with unlimited protein and free vegetables. Added fats will be encouraged to be limited and good choices in line with cardiocascular health advice. 8 participants will be randomised to this arm and will attend 4 group sessions to learn about the diet and matching insulin doses to this. These will be 1.5hrs once a week for the first 4 weeks of the intervention facilitated by a diabetes nurse and dietitian.
Sponsors
Capital and Coast District Health Board
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
Type 1 diabetes mellitus on a suitable insulin regime for carbohydrate and insulin manipulation
Exclusion criteria
Pregnant or breastfeeding women Unstable glycaemic control – HbA1c over 85
Outcome results
None listed