Remote ischemic preconditioning in obesity and diabetes

The effect of ischemic preconditioning in reducing inflammation and improving glucose homeostasis in obesity.

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612001117808

Enrollment

Registered

2012-10-19

Start date

2012-12-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To determine if preconditioning will have a beneficial effect on the metabolic derangements associated with obesity.

Interventions

Ischemic preconditioning will be induced by brief periods of limb ischemia (5mins) due to limb occlusion using a blood pressure cuff inflated to suprasystolic pressure and followed by 5 minutes of reperfusion for 4 cycles. This protocol of 4 cycles of occlusion and resotration of flow will be performed daily for 1 week in this study.

Study design

Allocation

Non-randomised trial

Primary purpose

Treatment

Eligibility

Sex/Gender

Male

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

Obesity BMI>30. Patients may not necessarily be diabetic.

Exclusion criteria

Drug therapy, smokers.

Outcome results