The effect of critical illness on fat absorption: comparative measurements in healthy volunteers

The effect of critical illness on enteral absorption of long chain triglycerides: comparative measurements in healthy volunteers

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612001077853

Enrollment

Registered

2012-10-09

Start date

2012-09-05

Completion date

2014-01-30

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to understand how healthy people absorb glucose (sugar) and lipids (fat) from their small intestine. This information can then be compared to information we are collecting about nutrient absorption in Intensive Care Unit patients. We hypothesize that absorption will be reduced in Intensive Care Unit patients compared to healthy volunteers.

Interventions

A 60ml Intraduodenal infusion at 120ml/hr of liquid nutrient mixed with 13C-triolein and 3-OMG infused into healthy volunteers

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Educational / counselling / training

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

17 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Healthy volunteers aged over 17 years.

Exclusion criteria

Inability to give informed consent. Contraindication to naso-duodenal feeding tube placement. Previous surgery on the oesophagus, stomach or duodenum. Any gastrointestinal disease. History of diabetes mellitus. Pregnancy.

Outcome results