None listed
Conditions
Brief summary
Patients with previous burns injuries are subject to abnormal pain processing responses compared to people who have never been affected by severe burns. We propose to run a pilot study which will demonstrate whether patients have ongoing abnormal pain responses. This would be determined by using a form of quantitative sensory testing which evaluates the integrity of pain pathways.
Interventions
Comparison of the information obtained from the non-traumatic nerve stimulation testing in burns patients to that of a group of matched controls who have also undergone identical nerve stimulation testing. The duration of testing is a single 60 minute session
Sponsors
Dr Alex Konstantatos
Eligibility
Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
Yes
Inclusion criteria
Burns Group 1. Burns injury sustained approximately 6 months prior which was 10% or greater in total body surface area not affecting the area of testing (ankle and leg) bilaterally 2. Alert and orientated 3. Ability to give informed consent 4. Able to cooperate with the nerve stimulation test 5. No current pain at rest Healthy Volunteer Group 1. Alert and orientated 2. Ability to give informed consent 3. Able to cooperate with the nerve stimulation test 4. Age average age of burns group +/- 5 years.
Exclusion criteria
Burns Group 1. Patient Refusal 2. 2. Burns/scarring to either of the two lower limbs below the knee 3. Inability to provide informed consent 4. Psychotic or paranoid disease 5. Chronic pain syndrome prior to burn 6. Acute/chronic brain syndrome 7. Current opioid therapy 8. History of untreated hypertension 9. History of diabetes 10. History of peripheral neuropathy Health Volunteer group 1. Patient Refusal 2. Inabilility to provide informed consent 3. Current or past history of psychotic or paranoid disease 4. Past history of chronic pain sydrome(s) 5. Acute/chronic brain sydrome 6. Recent (within 2 weeks) or current opioid use 7. History of untreated hypertension 8. History of diabetes 9. History of peripheral neuropathy
Outcome results
None listed