None listed
Conditions
Brief summary
Aim of the study is to evaluate the safety and efficacy of the use of a completly noninvasive device enabling the continuous measurement of blood pressure in patients with increased risk of cerebral malperfusion due to position changes (beach-chair position) under general anesthesia in compariosn to the standard anesthesia care. As a measure of safety/eficacy the proportion of time outside the near-normal ranges of blood pressures and hypotensive periods will be used in combination with assesment of mental abilities derrangements in the early postoperative course and potential postoperative morbidity.
Interventions
Maintanace of the near-normal pressure values throughout the surgery in beach-chair position (using fluids and vasopressors) with continuous noninvasive measurement of blood pressure obtained by the CNAP device (volume clamp method).
Sponsors
Dpt. of Anesthesia and Intensive Care of the Faculty of Medicine Plzen - Charles University Prague
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients undergoing surgery in beach-chair position (throid gland surgery, shoulder surgery/arthroscopy) General anesthesia Given and signed informed consent
Exclusion criteria
obvious perfusion abnormality on the side of measurement, vascular implants or known neuronal / neuromuscular disease on the side of measurement, peripheral edema
Outcome results
None listed