Cardiac Output Measurement using carbon dioxide inhalation in Open Heart Surgery Patients.

Cardiac Output Measurement using a Servo-Controlled CO2 Addition Fick Approach in Open Heart Surgery Patients with a Pulmonary Artery Catheter Placed.

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612001048875

Acronym

CO2 FICK cardiac output

Enrollment

Registered

2012-10-02

Start date

2012-12-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a study to find a new way to measure the cardiac output (CO), the amount of blood that leaves the heart every minute. Presently in order to measure CO we have to insert an expensive catheter into the heart which can bring complications. The present study aims to measure CO by inhaling small puffs of carbon dioxide which is normally excreted by the lung. By measuring the amount by which the blood concentration of CO2 rises we can know the blood flow through the lung.This is equal to the CO.

Interventions

In Fick CO2 cardiac output (CO) we need to measure CO2 production, and arterial and venous CO2 content of blood. CO2 production is measured in expired gases. Arterial CO2 content is measured using arterial blood gas from arterial line. Venous CO2 content is measured by adding CO2 to the inspired gas (mass flow-controller) at the CO2 production rate, causing arterial and end expired CO2 to rise to the mixed venous level.This measurement takes approximately 1 minute, measurements may take place ev

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

All consented patients undergoing elective open heart surgery and who have a pulmonary artery catheter placed.

Exclusion criteria

Pregnant women. Patients with a raised pulmonary artery pressure. Patients with Obstructive airways disease and raised pCO2. Patients with a raised intracranial pressure or primary cerebral disease.

Outcome results