Evaluation of a new technique for drug delivery to the esophageal wall in children with caustic esophageal stricture

Evaluation of the technical and clinical success of a novel endoscopic technique for Mitomycin C application in children with caustic esophageal stricture

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612001021864

Enrollment

Registered

2012-09-21

Start date

2011-04-06

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

we tried to innovate a new easy safe precise technique for topical mitomycin c application on caustic esophageal stricture aiming for decrease incidence of recuurance of stricture after endoscopic dilatation

Interventions

a new method for endoscopic mitomycin c application on esophageal stricture a) the dose of mitomycin c applied; 5ml (at a concentration of 0.4 mg/ml) b) the number of times applied; 1 to 3 times in 1 month interval " the 2nd and 3rd time will be done only if the child still symptomatic after 1st session" c) the mode of administration; topical application to esophageal stricture using rigid endoscopy and nelaton catheter for drug application d) the approximate duration of this procedure; 15 - 25

Study design

Allocation

Non-randomised trial

Primary purpose

Treatment

Eligibility

Sex/Gender

All

Age

1 Years to 8 Years

Healthy volunteers

Inclusion criteria

caustic esophageal stricture

Exclusion criteria

hypersensitivity to mitomycin c

Outcome results