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Assessment of health and functioning of New Zealand very preterm infants as young adults

Assessment of health and functioning of New Zealand very low birthweight infants born in 1986 as young adults compared with age-matched peers born at term.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12612000995875
Enrollment
350
Registered
2012-09-17
Start date
2013-02-01
Completion date
2016-11-01
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

We aim to assess the health and functional outcomes at 26-30 years of a large cohort of New Zealand babies born with very low birthweight (<1500g) in1986 and included in a prospective study. Very low birthweight babies account for nearly 2% of all births but 75% of neonatal intensive care unit workload. Although no NZ data exist, overseas studies suggest such young adults have increased risks of physical and health problems, educational underachievement and poorer social functioning than their peers. The group was last assessed at age 7- 8 years. We have now retraced 250 young adult survivors (77% of the group) and will bring them to Christchurch for two days of medical and psychological evaluations. A comparison group of 100 full term adults of the same age will also be assessed. Findings will inform health, education and social policies concerning very preterm survivors as well as future newborn care.

Interventions

Observation of growth parameters, total body fat, blood pressure, left ventricular function, endothelial dysfunction, respiratory function, visual function, creatine clearance, fasting insulin and glucose, cognitive and psychological functioning; assessments undertaken over 2 days at 26-30 years of age.

Sponsors

University of Otago
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
26 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Cohort group: Born in New Zealand in 1986 with birthweight less than 1500g Comparator group: Born in New Zealand in 1986 at full term

Exclusion criteria

For Comparator group only. Exclusion criteria are not born in New Zealand in 1986 at full term

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 4, 2026