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Does reducing intra-abdominal scar tissue formation after removal of a gastric band make subsequent obesity surgery quicker and safer?

Can the Sprayable Adhesion Barrier SprayShield (Trademark) reduce operating time during laparoscopic sleeve gastrectomy in patients who have previously had laparoscopic removal of a gastric band?

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000965808
Acronym
The SABROS (Sprayable Adhesion Barriers in Revisional Obesity Surgery) trial
Enrollment
52
Registered
2012-09-07
Start date
2012-10-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A randomised trial to determine whether using a sprayable adhesion barrier onto the operative field during removal of a gastric band will make a future laparoscopic sleeve gastrectomy quicker and safer due to reduced scar formation where the gastric band used to be.

Interventions

The intervention is performed at the end of the laparoscopic gastric band removal before removing all the laparoscopic ports. It is a Polymer Kit containing two precursor solutions, a polyethylene glycol (PEG) ester trilysine amine solution and a borate buffer solution. These are mixed together causing the precursors to link forming a synthetic, absorbable, hydrogel adhesion barrier. The reconstituted Polymer Kit syringes are attached to an applicator to allow the polymer to be sprayed onto the

The intervention is performed at the end of the laparoscopic gastric band removal before removing all the laparoscopic ports. It is a Polymer Kit containing two precursor solutions, a polyethylene glycol (PEG) ester trilysine amine solution and a borate buffer solution. These are mixed together causing the precursors to link forming a synthetic, absorbable, hydrogel adhesion barrier. The reconstituted Polymer Kit syringes are attached to an applicator to allow the polymer to be sprayed onto the operative field. Upon spraying, the polymer liquids mix and rapidly cross-link to form a thin, flexible, tissue adherent, hydrogel adhesion barrier.

Sponsors

Dr Michael Talbot
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients undergoing a staged conversion of a gastric band to a laparoscopic sleeve gastrectomy who meet the following criteria: 1 Any sex 2 Aged over 18 3 Proficient at speaking and understanding written English 4 Ability to understand the consent process

Exclusion criteria

1 Band erosion as reason for gastric band removal 2 Previous major surgery with suspicion of pre-existing adhesions 3 Pregnant or lactating 4 Renal or hepatic impairment 5 Known allergy to blue food colourings

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026