None listed
Conditions
Brief summary
This study will investigate the effects of exercise training in adults with congenital heart disease. Thirty patients with congenital heart disease will be randomised to either a 12 week exercise training program, or control group who will mainatin their usual activities, to review the effect on vascular function, cardiorespiratory fitness, muscle strength and quality of life.
Interventions
The exercise intervention will involve 12 weeks of exercise training involving aerobic and resistance modalities. Training will be performed for approximately one hour, three times a week. Initial sessions will be supervised by an exercise physiologist/physiotherapist and then the participant will exercise independently at a community gymnasium. Aerobic exercise will commence at 50% of the baseline VO2peak and progress to 70% of the VO2peak by the end of the intervention period. Resistance exerc
The exercise intervention will involve 12 weeks of exercise training involving aerobic and resistance modalities. Training will be performed for approximately one hour, three times a week. Initial sessions will be supervised by an exercise physiologist/physiotherapist and then the participant will exercise independently at a community gymnasium. Aerobic exercise will commence at 50% of the baseline VO2peak and progress to 70% of the VO2peak by the end of the intervention period. Resistance exercise will commence at 50% of the one-repetition maximum and progress to 70% of the one repletion maximum by the end of the intervention period.
Sponsors
Royal Perth Hospital
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Patients aged at least 18 years of age who had previously undergone a Fontan procedure, repaired tetralogy of Fallot, arterial switch operation for transposition of great arteries (including Mustard and Senning procedures), as well as patients with uncorrected congenital heart morphology.
Exclusion criteria
History of life-threatening arrhythmias in the absence of an automatic internal cardiac defibrillator Uncontrolled heart failure (ie, requiring hospitalization and/or intravenous medications within the last month) Severe aortic stenosis; resting peak systolic gradient >50 mm Hg Severe pulmonary stenosis, resting peak systolic gradient >50 mm Hg Severe systemic atrioventricular valve regurgitation Unmedicated systemic hypertension (>165/100mmHg) Pregnancy, or planning to become pregnant during the course of the study
Outcome results
None listed