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Effects of mammary reduction surgery in women with macromastia in respiratory system impedance and pulmonary function

Effect of mammary reduction in the pulmonary function and mechanics for healthy women with macromastia: Intra and post-operative evaluation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000904875
Enrollment
25
Registered
2012-08-24
Start date
2004-12-12
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients with macromastia were submitted to mammary reduction and we assessed the impact of this procedure in respiratory system impedance. We hypothesized that this reduction could improve the respiratory system impedance. All patients were recruited in Brazil.

Interventions

The measuring of compliance and oxygenation were carried out in four stages. After 10 minutes of mechanical ventilation, before the start of surgery, static compliance was measured and hemogasometry was carried out. Immediately after the first stage, a recruitment maneuver was applied and 10 minutes later static compliance was measured and hemogasometry was carried out to complete the second stage. At the end of the surgery, static compliance was measured and hemogasometry was carried out again

The measuring of compliance and oxygenation were carried out in four stages. After 10 minutes of mechanical ventilation, before the start of surgery, static compliance was measured and hemogasometry was carried out. Immediately after the first stage, a recruitment maneuver was applied and 10 minutes later static compliance was measured and hemogasometry was carried out to complete the second stage. At the end of the surgery, static compliance was measured and hemogasometry was carried out again. Then a new recruitment maneuver was applied to complete the third stage. Ten minutes later, static compliance was measured and hemogasometry was carried out to complete the fourth stage. The mammary reduction was made by bilateral resection of the breast - super-medial, pediculo's technique which is used normally to reduce the breast symmetrically. The lung and the chest have a impedance which can be measured by the compliance and resistence. The reduction of the breast was measured by the weight and the respiratory system impedance was measured with a inspiratory pause at the respirator. Every surgery had a mean of 270 minutes.

Sponsors

Professor Edgard Santos University Hospital
Lead SponsorHospital

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Patients with macromastia and physical status by American Society of Anesthesiology (ASA) = 1

Exclusion criteria

Patients with ASA > 1 Patients classified with difficult airway Patients with Allen test positive Patients with active disease in respiratory system

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026