None listed
Conditions
Brief summary
South Asians have a higher than average risk of coronary heart disease. The reasons for this are unclear but physical inactivity and/or poor responsiveness to exercise may play a role. The proposed study compared the prior effect of a single bout of running on CHD risk markers in South Asian and European men.
Interventions
The study consisted of two, 2-day trials (exercise and control). Each trial involved two, nine hour days in a laboratory (8:00 am to 5:00 pm). Participants performed a one-hour treadmill run at approximately 70% of maximum oxygen uptake on day 1 of the exercise trial. All exercise sessions were supervised on a one to one basis by an exercise physiologist. Participants rested on day 1 of the control trial. During day 2 of both trials participants ate standardised meals for breakfast (8:00 am) and
The study consisted of two, 2-day trials (exercise and control). Each trial involved two, nine hour days in a laboratory (8:00 am to 5:00 pm). Participants performed a one-hour treadmill run at approximately 70% of maximum oxygen uptake on day 1 of the exercise trial. All exercise sessions were supervised on a one to one basis by an exercise physiologist. Participants rested on day 1 of the control trial. During day 2 of both trials participants ate standardised meals for breakfast (8:00 am) and lunch (12:00 pm). These meals consisted of white bread, butter, cheese, mayonnaise, crisps, chocolate milk shake powder and high fat milk. The macronutrient content of these meals was 57% fat, 32% carbohydrate and 11% protein and each meal provided 60 kJ (14.3 kcal) per kg body mass for a 70 kg participant. Fourteen, 9 mL venous blood samples were collected during day 2 of each trial via a cannula. Participants were assigned to the trials in a random order and trials were separated by at least one week.
Sponsors
Loughborough University
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
South Asian and Eurpoean participants.
Exclusion criteria
Smoking; Known history of cardiovascular disease, metabolic disease or dyslipidaemia; Not dieting or following extreme dietary habits; Not on medication affecting digestion or metabolism – medical or illegal
Outcome results
None listed