None listed
Conditions
Brief summary
To determine whether the administration of large or small volumes of fluid to patients underoing major elective abdominal surgery influences lenght of stay and outcome
Interventions
Patients will be randomised to receive either a high or low volume perioperative intravenous fluid protocol. The use of goal directed devices will be controlled for in the statistical analysis, but their use is not part of the actual protocol . The Restrictive group will be considered the Control group for the purpose of the study design. The Liberal group will receive 10mls / kg at induction, 8 mls per kg per hour intraoperatively, and then 1.5 mls per kilogram intravenously postoperatively. Th
Patients will be randomised to receive either a high or low volume perioperative intravenous fluid protocol. The use of goal directed devices will be controlled for in the statistical analysis, but their use is not part of the actual protocol . The Restrictive group will be considered the Control group for the purpose of the study design. The Liberal group will receive 10mls / kg at induction, 8 mls per kg per hour intraoperatively, and then 1.5 mls per kilogram intravenously postoperatively. The intention is to cease all fluids ASAP.
Sponsors
Health Department of Western Australia
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Elective Major Abdominal Surgery At least one night in hospital High Surgical Risk
Exclusion criteria
Renal Failure Coagulopathy
Outcome results
None listed