None listed
Conditions
Brief summary
This trial will be looking at patients who have osteoarthritis of the knee. Such patients will be referred by their doctor for knee arthroscopy. These patients usually have mild-moderate osteoarthritis of the knee and will undergo arthroscopy to reduce their pain and improve function. At the moment, when the arthroscopy is performed, a certain fluid pressure is used. This trial will try using a lower pressure and compare it with the current standard. It is hypothesised that patients who get the lower pressure will have less pain, less bone marrow swelling and increased degree of function. These are the three areas the trial will be assessing and will be comparing this with patients who get the current standard pressure, 6 weeks after the arthroscopy.
Interventions
Patients will undergo arthroscopy as per the usual standard of this procedure. What will vary will be the pressure of the fluid used to visualise the joint with the arthroscopic device. In this case the fluid pressure will be run at 30mmHg as opposed to the standard pressure which can vary amongst different health centres but in this case will be 80mmHg. The length of the procedure can vary from patient-to-patient depending on what is discovered during the procedure by the surgeon. It is a day s
Patients will undergo arthroscopy as per the usual standard of this procedure. What will vary will be the pressure of the fluid used to visualise the joint with the arthroscopic device. In this case the fluid pressure will be run at 30mmHg as opposed to the standard pressure which can vary amongst different health centres but in this case will be 80mmHg. The length of the procedure can vary from patient-to-patient depending on what is discovered during the procedure by the surgeon. It is a day surgery procedure with the length of this lower pressure arthroscopy taking the same length of time as standard pressure.
Sponsors
Stewart Hunt
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Patients with osteoarthritis who have been diagnosed via medical imaging and in whom a total knee replacement is not indicated. 2. Indication for arthroscopy is either for meniscal or cartilage debridement. 3. Patient can weight bear as tolerated post procedure.
Exclusion criteria
1. Inability to consent. 2. Bone marrow oedema pre-procedure. 3. Requirement of additional intra-operative procedures to be performed (e.g. deemed necessary by the operating surgeon due to unanticipated circumstances) 4. Inadequate visualisation of the knee joint intra-operatively requiring the operating surgeon to adjust the joint fluid pressure from what has been allocated for this patient.
Outcome results
None listed