None listed
Conditions
Brief summary
Air is currently used as the insufflation agent during colonoscopy to allow for visualisation & detection of colorectal lesions. Recently, there has been a trend towards introducing carbon dioxide as an alternative agent as this reportedly reduces post-procedural discomfort. There have been several trials internationally that have revealed this trend, but none so far in Australia. Our aim is to randomise adult patients with intact colons (those who have not undergone any bowel resection) to either air and carbon dioxide with the aim of assessing and comparing their post-procedural discomfort using a visual analog scale from 0 to 10. Other information such as the time to completion of the procedure and time to reach the end of the colon (that is the caecum) will be obtained. We propose that the use of carbon dioxide as the insufflation agent during colonoscopy is better in terms of improvement of post-procedural discomfort than air.
Interventions
Randomisation of Carbon Dioxide versus Air as the insufflation agent during colonoscopy & impacts this has on post-procedural pain/discomfort
Patients presenting for colonoscopy with an intact colon (that is not had any previous bowel resections) will be randomised through concealed envelopes to either carbon dioxide or air as their insufflation agent during their procedure. Once the procedure is completed, the patient will be asked to rate their pain using a Visual Analog Scale (VAS) from 0-10
Randomisation of Carbon Dioxide versus Air as the insufflation agent during colonoscopy & impacts this has on post-procedural pain/discomfort Patients presenting for colonoscopy with an intact colon (that is not had any previous bowel resections) will be randomised through concealed envelopes to either carbon dioxide or air as their insufflation agent during their procedure. Once the procedure is completed, the patient will be asked to rate their pain using a Visual Analog Scale (VAS) from 0-10 by a blinded trained member of the nursing staff. Scoring of pain will take place at 15, 30 & 60 minutes post procedure. Air or carbon dioxide will ONLY be used for the duration of the colonoscopic procedure for which the patient has been consented for. The agent will be used to insufflate the colon to enable the procedure to be performed; the duration will be until completion of the colonoscopy as deemed by the proceduralists. The amount insufflated per agent during a procedure is not routinely recorded (as it makes no physiological difference) and the time for the colonoscopy varies accordingly (in fact, it is one of our secondary endpoints - to measure the time to completion and determine if a difference exists between the two agents). There will be otherwise no difference as to what is performed during a 'routine' colonoscopy.
Sponsors
Western Health
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Any patient over the age of 18 undergoing colonoscopy for any indication in absence of previous colorectal bowel resection.
Exclusion criteria
Inability to consent Previous colorectal bowel resection (non-intact lower GI tract)
Outcome results
None listed