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Pilot study: To determine the effect of physiotherapy on neck stiffness following radiotherapy for Nasopharyngeal Carcinoma

The effect of physiotherapy versus exercise on neck fibrosis for post-irradiated patients with Nasopharyngeal Carcinoma – A pilot randomised trial

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000839808
Enrollment
100
Registered
2012-08-09
Start date
2012-06-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The study is the first trial investigating the effect of physiotherapy on neck muscle fibrosis for post irradiated patients with nasopharyngeal carcinoma, NPC. Exercise and education are commonly received by patients as a means of self empowerment. These treatments will be compared. Patients with NPC are studied because they are usually young and are the breadwiner of the family in a Chinese society. The study also bears significant meaning because musculoskeletal complications post radiotherapy are commonly neglected globally.

Interventions

Patients will receive a maximal of 3 months of weekly individual multimodal physiotherapy of 1 hour session composing of neck strengthening exercise, passive stretching and education.

Sponsors

Prince of Wales Hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

Patients who have: a) completed their course of radiotherapy more than three years ago; b) neck discomfort/pain, neck stiffness, and/or arm symptoms; and c) whose disease is in remission.

Exclusion criteria

Patietns will be excluded from the study if they a) have signs of active metastasis; b) have received surgical intervention for their NPC; c) are illiterate and unable to complete the questionnaire by themselves; d) have a recent (within one year) history of trauma to the neck; and e) have already been entered into another clinical trial.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026