The chronic effects of Bacopa on cognitive performance in Alzheimer's patients - A pilot study

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612000785808

Enrollment

Registered

2012-07-24

Start date

2012-08-15

Completion date

Unknown

Last updated

2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The goal of this study is to investigate the efficacy of Bacopa as an adjunctive therapy to existing pharmaceutical treatments for Alzheimers patients. The study will test individuals diagnosed with mild to moderate Alzheimer's Disease, in a double blind, placebo controlled, parallel groups design. Particpants will either take Bacopa monniera for 90 days or a placebo for 90 days. Participants will attend an initial pre-screening and pratice session, baseline session and one follow-up testing session following 90 days of supplementation. During these session, participants will be required to complete several cognitive tests, which have been widely used to assess both enhancement and impairment of human cognitive performance. Mood and quality of life will also be assessed. It is hypothesised that measures of attention, processing speed and memory will improve in the Bacopa group relative to the placebo group. A further aim of the study is to investigate differences in mood and quality of life in the Bacopa treatment group relative to placebo.

Interventions

Bacopa Monniera (Brahmi), 160mg per tablet, 2x Tablets to be consumed orally, daily for 90 day duration

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Healthy volunteers

Inclusion criteria

Diagnosis of mild to moderate Alzheimer's disease Aged 60 and above

Exclusion criteria

less than 60 years of age History of, or current psychiatric illness Neurological diseases (other than Alzheimers) Suffering from Endocrine, gastrointestinal or bleeding disorders A history of chronic illness or infection Pregnant or lactating current use of medications including; anticoagulants, antidepressants, anti-psychotics, anxyolitics, anti-parkinsons. current use of illicit drugs, cognitive enhancing drugs, or vitamin and herbal supplements

Outcome results