None listed
Conditions
Brief summary
Signal Detection Theory (SDT) provides a method that measures discriminability (d’) of any stimulus (signal) without response bias (c) effect . The aim of the study was to adapt SDT approach to gastroesophageal reflux disease (GERD) diagnosis in order to develop a new analysis method for temporal relationship between reflux and symptom for 24 hour impedance-pHmeter monitoring data. We have considered reflux and symptom as signal and response respectively in this context. In conclusion, SDT approach using 1 min time window to GERD diagnosis provides us a simple, quantitative measure of reflux-symptom relationship that appears to more accurate than SAP index for MII-pH monitoring analysis.
Interventions
24 hour ambulatory impedance-pHmeter monitoring. A thin catheter (diameter 2.1 mm) which have attached a data logger (a walkman-sized portable electronic recording device) passed through a nostril and positioned according to lower esophageal sphincter's upper border. Patients then returned home with instructions to press buttons which are located on the data logger for symptoms, meal intake times and sleeping. They were encouraged to carry out normal daily activities without dietary restrictions
24 hour ambulatory impedance-pHmeter monitoring. A thin catheter (diameter 2.1 mm) which have attached a data logger (a walkman-sized portable electronic recording device) passed through a nostril and positioned according to lower esophageal sphincter's upper border. Patients then returned home with instructions to press buttons which are located on the data logger for symptoms, meal intake times and sleeping. They were encouraged to carry out normal daily activities without dietary restrictions. At the completion of the study (that is 24 hour), the catheter is removed and the data logger is uploaded to the computer for analysis.
Sponsors
Marmara University
Study design
Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Diagnosis
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Patients with heartburn and/or gastric regurgitation
Exclusion criteria
Gastrointestinal surgery history
Outcome results
None listed