Effect of potassium supplementation on blood vessel function

Acute effect of potassium supplementation on endothelial function in healthy populations

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612000753853

Enrollment

Registered

2012-07-16

Start date

2012-08-08

Completion date

2012-11-16

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to determine the effect of potassium supplementation in a single meal on blood vessel function. A high potassium intake is associated with reduced risk of heart disease however effect of potassium on blood vessel function is not known. We propose potassium supplementation will improve blood vessel function.

Interventions

Potassium supplemented soup meal (36mmol potassium) to be consumed within 15minutes versus control with 7day washout between visits

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

BMI greather than 18kg/m2 and less than 27kg/m2 SBP <90mmHg DBP<130mmHg weight stable for 6months

Exclusion criteria

Use of antihypertensive medication, systemic steroids, folate supplementation or non-steroidal antiinflammatory drugs. Metabolic disease such as liver or kidney disease. Treated hypertension. Previous clinical cardiovascular disease. Unable to comprehend protocol.

Outcome results