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Rehabilitation in Patients Hospitalised with An Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Evaluation of exercise training versus usual care on exercise capacity, muscle strength and functional performance in patients hospitalised with an acute exacerbation of Chronic Obstructive Pulmonary Disease.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000745842
Acronym
AECOPD: Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Enrollment
38
Registered
2012-07-13
Start date
2013-07-30
Completion date
2014-08-04
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The present study aims at investigating the effects of a standardised exercise training program that comprises of walking and resistance exercises on exercise capacity, quadriceps muscle strength and functional performance in patients hospitalised with an AECOPD. Study hypotheses In patients with COPD who are hospitalised with an acute exacerbation of their disease, those who are allocated to the treatment group will show a significantly greater improvement in 2MWD, quadriceps muscle force, performance in the STST and TUG, and physical activity compared to the control group.

Interventions

Patients allocated to the treatment group will receive two individual training sessions daily during the five weekdays, in which the morning session will be supervised, and the afternoon session will be unsupervised. The training sessions will comprise of walking and resistance exercises and will be carried out by a trained physiotherapist. The training will commence within 48 hours of admission until the patients are allowed to be discharged from the hospital. We expect each session (supervised

Patients allocated to the treatment group will receive two individual training sessions daily during the five weekdays, in which the morning session will be supervised, and the afternoon session will be unsupervised. The training sessions will comprise of walking and resistance exercises and will be carried out by a trained physiotherapist. The training will commence within 48 hours of admission until the patients are allowed to be discharged from the hospital. We expect each session (supervised or unsupervised) to take no longer than 30 minutes (inclusive of rests). Resistance training includes sit to stand, half squats and step exercises. Initial prescription will be determined by one set of individualised number of repetition based on the baseline Sit-To-Stand-Test score. The exercise prescription will be increased by one set on every second day of training. Walking training will be prescribed based on the baseline two-minute walk distance (2MWD) and progressed on every second day of training by increasing the distance walked during each session by 20%.

Sponsors

School of Physiotherapy and Curtin Health Innovation Research Institute
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No

Inclusion criteria

Patients who are admitted with an AECOPD.

Exclusion criteria

(i) any contraindication to exercise as listed by the American College of Sports Medicine (ii) hospitalisation within the previous 14 days (iii) inability to understand or speak English or Malay

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026