Role of oral ketamine and dexmedetomidine in adults burns dressing. A double blind randomised cross over study.

Role of oral ketamine and dexmedetomidine in adults burns dressing for evaluating safety and efficacy:A double blind randomised cross over study

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612000700831

Enrollment

Registered

2012-06-29

Start date

2010-08-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To evaluate the analgesic effect and safety of dexmedetomidine and ketamine in adults during burns dressing changes

Interventions

Patients will be given morphine intra muscular( IM) 0.1 mg/kg;; local anesthetic soaked gauzes will be applied on the wounds oral ketamine 5 mg/kg will be given ;visual analogue scale( VAS) score; sedation score; vital parameters will be recorded; the next day patient cross over to dexmedetomidine group; they will receive morphine similar to the previous day and dexmedetomidine 4ug/kg all the above parameters recorded

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

15 Years to 40 Years

Healthy volunteers

Inclusion criteria

adult patients with burns 20 to 50 % body surface area

Exclusion criteria

facial burns preventing oral intake

Outcome results