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A randomised trial of quality of recovery in ambulatory surgical patients receiving general anaesthesia versus regional anaesthesia

A randomised trial of quality of recovery in ambulatory adult surgical patients receiving general anaesthesia versus general anaesthesia supplemented with regional anaesthesia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12612000688886
Enrollment
62
Registered
2012-06-27
Start date
2014-04-01
Completion date
2015-09-01
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Ambulatory surgery is performed as an outpatient day-only procedure, and is considered minor surgery. Anaesthesia for this type of surgery can be with general anaesthesia (GA) only, or GA in combination with regional anaesthesia (RA). However, while it is assumed that outpatient surgery constitutes minor surgical stress, there are sufficient case series observing severe cognitive dysfunction and poorer than expected functional recovery even after brief surgery. Anaesthetists have used RA techniques on the assumption that an effective nerve block allows a reduction in GA doses, better and prolonged analgesia, and a positive influence on post-operative recovery. This study will help anaesthetists determine if anaesthetic choices will lead to better outcomes for their patients undergoing minor ambulatory surgery. The primary endpoint of this study is the incidence of cognitive recovery at day 3 between groups. Secondary endpoints will be recovery in other domains, over time.

Interventions

Ambulatory adult patients undergoing upper limb surgery receives general anaesthesia alone, or general anaesthesia with regional block (brachial plexus block). The PQRS (Postoperative Quality of Recovery Scale) tool is used for multiple domain characterisation of quality of recovery for both groups. Baseline data is obtained pre-operatively, in the Post-Anaesthesia Care Unit (PACU), and post-discharge

Sponsors

Liverpool Hospital - South West Sydney Local Health District
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

adult ambulatory upper limb surgery lasting 1-3hours duration

Exclusion criteria

unable to provide informed written consent.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026