Comparison between the effect of probiotic cheese and probiotic yoghurt on blood lipids in healthy adult volunteers

Comparison between the effect of probiotic cheese and probiotic yoghurt on blood lipids in healthy adult volunteers: a triple blinded randomized trial

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612000623897

Enrollment

180

Registered

2012-06-08

Start date

2012-04-02

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Objectives: The purpose of current study was to compare the effect of Probiotic cheese with Probiotic yoghurt consumption on lipid profile during a 7 wk period. Design: It was a triple blinded parallel randomized controlled trial in Tehran, Iran. 180 volunteers aging 18 – 65 will participate. Participants will be randomly assigned into three 60-person balanced groups and consume 30 g Probiotic cheese containing Lactobacillus acidophilus LA5 and Bifidobacterium lactis BB12 daily (intervention 1), 100 g of Probiotic yoghurt (intervention 2) and none of the above (control group). Fasting blood samples and anthropometric measurements will be collected in the beginning and after the consumption period at the Pathobiology Laboratory Center and SRBIAU Nutrition clinic, respectively.

Interventions

Arm1: 30 g Probiotic feta ultra filtered cheese containing Lactobacillus acidophilus LA5 and Bifidobacterium lactis BB12 with the dosage of 5 × 106 CFU to consume in the daily diet. Duration of consumption: 7 weeks/ everyday Arm2: 100 g Probiotic yoghurt containing Lactobacillus acidophilus LA5 and Bifidobacterium lactis BB12 with the dosage of 5 × 106 CFU to consume in the daily diet. Duration of consumption: 7 weeks/ everyday

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

Healthy condition, aged 18-65, not being lactose intolerance and willingness to participate in the study.

Exclusion criteria

Smoking, alcohol consumption during the study, pregnancy or breast feeding, being a professional athlete, taking supplements or any sort of drugs specially antibiotics, consumed any Probiotic product during the last month before the intervention start, having kidney or inflammatory intestinal diseases, having thyroid disorders, having any liver or immunodeficiency diseases.

Outcome results