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Appraisal of the LIFT and BioLIFT procedure: initial experience and short-term outcomes of patients with complex anal fistula.

Appraisal of the LIFT and BioLIFT procedure: initial experience and short-term outcomes of patients with complex anal fistula.

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12612000605897
Enrollment
20
Registered
2012-06-06
Start date
2012-06-10
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The surgical management of anal fistulas remains in an evolutionary phase. A new sphinctersaving technique known as the LIFT (ligation of intersphincteric tract) procedure has gained growing interest. Early results together with reports from other authors have been promising with 57-94% success and minimal complications. The use of a bioprosthetic device has been suggested to augment the LIFT procedure (BioLIFT). The purpose of this study is to evaluate and compare outcomes of patients where repair of transphincteric anal fistula was performed using LIFT and BioLIFT techniques. Patients who have undergone LIFT or BioLIFT procedure from 2011-current, by a single surgeon will be retrospectively reviewed. Case notes will be retrieved and data entry performed. Statistical analysis of outcomes will be assessed. Outcomes measures of complications, recurrence, physiology studies performed pre and post operative, will be evaluated.

Interventions

The purpose of this study is to evaluate and compare outcomes of patients where repair of transphincteric anal fistula was performed using LIFT and BioLIFT techniques. This is a retrospective review of patient who had undergone the LIFT and BioLIFT procedure. Data will be collected from the hospital medical records. Followup details will be obtained from surgeon's private rooms. The 'intervention' group would be patient who had the BioLIFT procedure for treatment of transphincteric anal fistul

The purpose of this study is to evaluate and compare outcomes of patients where repair of transphincteric anal fistula was performed using LIFT and BioLIFT techniques. This is a retrospective review of patient who had undergone the LIFT and BioLIFT procedure. Data will be collected from the hospital medical records. Followup details will be obtained from surgeon's private rooms. The 'intervention' group would be patient who had the BioLIFT procedure for treatment of transphincteric anal fistula, from 2011 to current, by a single surgeon. The BioLIFT procedure involves the use of a bioprosthetic device to augment the LIFT (Ligation of Intersphincteric Fistula Tract) procedure.

Sponsors

Dr Peter Lee
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients: Patients will be retrieved from a single surgeon logbook. Inclusion criteria of patients analysed : 1. Patients with diagnosis of complex suprasphincteric anal fistula of cryptoglandular in origin 2. All patients, both male and female who are >18years of age with perianal sepsis 3. Crohn’s patients as a separate subset analysis

Exclusion criteria

Exclusion criteria: 1.Patients < 18years of age 2.Defunctioning stomas 3.Patient with noncryptoglandular fistula, Tuberculosis and malignant fistulas

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026