None listed
Conditions
Brief summary
The aim of this project is to determine the effects of fructose feeding on fat-induced weight gain in humans. The hypothesis is that the satiety effect will be greater in those consuming a high fat meal with fructose as oppose to water or non-sugary drink.
Interventions
Group 1) Soda Water Group 2) Soda Water + artificial sweetener Group (Splenda) 3) Soda Water + 15% fructose Group 4) Soda Water + 15% glucose (all groups containing lemon flavouring). All groups will be asked to consume a Big Mac Meal. The volume of the drink that will be administered is 375mls. The meal and drink will only be administered once simutaneously over a period over 15mins (from t=0 to t= 15). The participants will be offered some light refreshments at the end of each visit. Each
Group 1) Soda Water Group 2) Soda Water + artificial sweetener Group (Splenda) 3) Soda Water + 15% fructose Group 4) Soda Water + 15% glucose (all groups containing lemon flavouring). All groups will be asked to consume a Big Mac Meal. The volume of the drink that will be administered is 375mls. The meal and drink will only be administered once simutaneously over a period over 15mins (from t=0 to t= 15). The participants will be offered some light refreshments at the end of each visit. Each participant is required to complete all 4 test groups (one group per visit). The order of the groups are randomised.
Sponsors
The University of Melbourne
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Individual with stable weight (i.e. no more than 3kg gain/loss in the last 3 months) and no major health problems.
Exclusion criteria
People whose primary language is other than English (LOTE), Women who are pregnant and the human foetus, Children and/or young people (ie.<18 years), People highly dependent on medical care and people with a cognitive impairment, an intellectual disability or a mental illness.
Outcome results
None listed