None listed
Conditions
Brief summary
It is well established that industrial trans fatty acids (TFA) are harmful to health however, little is known about the effects of the natural TFA found in dairy. Some like the FDA feel that all TFA is harmful and have recommended that intake be limited as much as possible. An observational study by CVRU suggests that dairy TFAs may be harmful to cardiac health. Conversely a recent Harvard University observational cross sectional study observed that these isomers reduced insulin resistance. This interventional study is a randomised clinical study in 180 participants and assesses the effects of changing dairy intake on TFA, inflammatory markers, lipids, insulin resistance and anthropomorphic parameters.
Interventions
Arm 1- increased dairy consumption by 2 standards servings/day
Arm 2- eliminate all dairy as much as possible
Arm 3- no change
for 4 weeks. All participants had a one to one session with a study co ordinator with exerience in giving dietary advice on on one. A sheet with tips on how to change dairy intake(when applicable) was also given to all participants
Sponsors
auckland city hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Aged over 18 years of age Able to give informed consent
Exclusion criteria
1. Unwilling to trial dietary intervention 2. lactose intolerant/milk allergy 3. pregnant/lactating 4. Known vitamin D deficiency or hypocalcaemia 5. Osteoporosis. 6. Inflammatory conditions e.g. rheumatoid arthritis 7. On a statin 8. Known cardiovascular disease (stroke, ischemic heart disease, peripheral vascular disease)
Outcome results
None listed