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A Pilot Study of Topical Honey for the Treatment of Psoriasis

In adult patients with psoriasis is topical medical-grade honey acceptable and as good as or better than aqueous cream for reducing the severity of psoriasis lesions?

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000562875
Enrollment
15
Registered
2012-05-25
Start date
2012-07-25
Completion date
2012-11-09
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

There are reasons to believe that medical grade-honey applied directly to skin may be an effective treatment for psoriasis. In this study 15 adults with psoriasis will apply honey to an psoriasis lesion on one arm and aqueous cream to a matched lesion on the other overnight, every night for two weeks. After two weeks the lesions will be assessed to look at changes in severity. Participants will also be asked about their experience of using honey. This trial will provide useful information on the practicalities of topical honey as a treatment for psoriasis. It will also give an initial signal as to whether honey may be effective.

Interventions

Topical medical grade honey applied to lesion overnight for 2 weeks. Subjects will apply sufficient honey to form a thin film over the affected area.

Sponsors

Medical Research Institute of New Zealand
Lead SponsorCharities/Societies/Foundations

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Aged 16 or over at the time of enrolment Psoriasis involving the upper or lower limbs Bilateral lesions, to allow comparison

Exclusion criteria

Requirement for topical or systemic corticosteroids, as judged by treating doctor Requirement for antibiotic therapy, as judged by treating doctor Known or suspected allergy to honey or dressings Any other condition which, at the investigators discretion, it is believed may present a safety risk or impact the feasibility of the study or the study results

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026