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Glycemic responses to glucose and rice in people of Chinese and European ethnicity

Determinants of postprandial glycaemia and glycaemic index of five rice varieties and a sucrose beverage in healthy people of Chinese or European descent

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000519853
Enrollment
60
Registered
2012-05-16
Start date
2010-03-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of the project is to compare postprandial glycaemia and the glycaemic index of five types of rice and a sucrose product available in New Zealand between Chinese and Caucasian groups. Chewing and salivary alpha amylase activity will be tested as possible determinants of the postprandial response.

Interventions

The Glycaemic Index (GI) provides a measure of a person’s rise in blood glucose following consumption of a test food relative to a reference food. Data from some observational studies suggest that consuming high GI food is a risk factor for obesity and type II diabetes. Although more than 60% of the world’s population with diabetes will come from Asia, studies of GI in Asian people are scarce. White rice is a staple food in Asia and a major determinant of GI in the Asian diet. In the clinical se

The Glycaemic Index (GI) provides a measure of a person’s rise in blood glucose following consumption of a test food relative to a reference food. Data from some observational studies suggest that consuming high GI food is a risk factor for obesity and type II diabetes. Although more than 60% of the world’s population with diabetes will come from Asia, studies of GI in Asian people are scarce. White rice is a staple food in Asia and a major determinant of GI in the Asian diet. In the clinical setting in New Zealand, dietitians recommend patients consume varieties of rice shown to have a low GI value. However, published GI values are largely obtained in other countries using non-Asian test subjects. The relevance of GI values determined in Caucasian people for Asian consumers is questionable because we have found ethnic differences in GI. The rice varieties to be tested are generally available in New Zealand supermarkets and are jasmine, parboiled, basmati, brown and Doongara. The sucrose is LoGiCane sugar. Testing will be undertaken over a period of 6 weeks. Test days will be non-consecutive and be undertaken 2 to 3 days per week. The trial is measuring the acute response of blood glucose immediately following a test meal served in portions containing 50g available carbohydrate. Equal numbers of male and female volunteers will be enrolled within age brackets (10 aged 18-30y, 10 aged 31-40y, and 10 aged 41-50y) for each ethnicity. The foods will be tested in sequence but the entry point of a participant into that sequence will be randomized. As such, ethnic-specific diet plans are not required although there are recommendations regarding standardisation of evening meals and exercise prior to each test day and exercise on the morning of the test day. Postprandial glycaemia will be measured using capillary blood and a Hemocue instrument. Extent of chewing will be determined by having the participants chew and expectorate a weighed sample and then rinsing over a laboratory sieve in order to measure the proportion of finely chewed rice. Saliva samples will be collected for the determination os salivary alpha-amylase activity using a proprietary kit.

Sponsors

University of Otago
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

Healthy people of Chinese descent both of whose parents were of the same race. Healthy people of European descent.

Exclusion criteria

People diagnosed with chronic disease including diabetes mellitus, cardiovascular disease, cancer, and diseases of the digestive system; who are taking any medications that affect glucose tolerance; that suffer from food allergies; and women who are pregnant.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 20, 2026