Effect of vitamin D supplements on cardiometabolic risk and quality of life in premenopausal women: a randomized control trial

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Recent evidence has indicates that apart of vitamin D classical role in musculoskeletal diseases, vitamin D deficiency also associated with cardiometabolic risk factors such as hypertension, diabetes mellitus and hypercholesterol. Although Malaysia is a sunshine-abundant country, recent studies have found that the prevalence of vitamin D deficiency is significantly high. However, no study done to measure its effect on cardiometabolic risk factors in Malaysia with very limited clinical trials globally to measure the relationship between vitamin D and both the cardiometabolic risk and quality of life. This is a parallel randomized placebo control trial that investigating the effect of vitamin D supplements on both the cardiometabolic risk and quality of life in urban healthy population in Kuala Lumpur, Malaysia. The objective of this study is to investigate whether vitamin D supplements can reduce the cardiometabolic risk and quality of life in urban premenopausal women with vitamin D deficiency.