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Sodium excretion and dietary intake in people with coeliac disease, an observational study.

Sodium excretion and dietary intake in people with coeliac disease, an observational study.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12612000424808
Enrollment
33
Registered
2012-04-16
Start date
2012-05-01
Completion date
2012-12-10
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

High sodium intake, as measured by urinary sodium excretion, is associated with increased bone loss (Divine, 1995). In Australia, the national target for salt intake was achieved by only 6% of men and 36% of women (Beard, 1997). A positive relationship exists between urinary sodium and urinary calcium excretion, with repeated studies showing that a high level of salt in the diet increases calcium excretion (Ilich, 2000). Other studies have recognised that people following a gluten-free diet have a lower bone mineral density, likely related to calcium malabsorption (Scott, 2000). It is not clear from the research how much sodium is ingested by those following a gluten free diet.

Interventions

The aim of the research is to determine the level of sodium excretion and the food sources in the diet of people with coeliac disease. Participants will be provided with digital kitchen scales and asked to provide a three-day weighed food record. They will also be asked to provide a 24-hour urine sample in order to measure sodium excretion. A DEXA scan of forearm, hip and lumbar spine will be taken on one occasion to measure bone density.

Sponsors

University of South Australia
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Men and women over the age of 18, with diagnosed coeliac disease.

Exclusion criteria

Exclusion criteria would include those with major metabolic illness such as kidney, liver or heart disease.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026