comparison of benefit of tramadol-only treatment and tramadol+gabapentin treatment in patient with lumbar disc herniation after epidural steroid injection

a clinical trial to compare the effect of tramadol only treatment with tramadol + gabapentin treatment on the clinical course, serotonin level, and inflammatory response for patients with lumbar disc herniation after epidural steroid injection

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12612000408886

Enrollment

Registered

2012-04-12

Start date

2011-09-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study was to compare the effects of tramadol-only treatment and tramadol+gabapentin treatment on clinical course, serotonin level and inflammatory response in patients with lumbar disc herniation after epidural steroid injection

Interventions

All the patients received a single dose steroid and local anesthesia mixture epidurally via the lumbar approach In study group (Group T, (Tramadol, n=20). Injection dose was adjusted to 10 ml from triamcinolone acetonide, and 0.125% bupivacaine mixture. Oral dose of 100 mg/day tramadol was added to the treatment of patients in group T during study period (15 days).

Study design

Allocation

Randomised controlled trial

Primary purpose

Treatment

Eligibility

Sex/Gender

All

Age

20 Years to 55 Years

Healthy volunteers

Inclusion criteria

Herniated lumbar disc, epidural steroid injection

Exclusion criteria

bilateral root pressure findings, neurologic deficit, previous lumbar vertebral surgery history, serious cardiac, pulmonary, hematological, gastrointestinal, and liver or kidney disease, glaucoma, urinary retention, statin group drug usage, hormone replacement therapy, and known allergy to the study drugs

Outcome results