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Screening Education And Recognition in Community pHarmacies of Atrial Fibrillation to prevent stroke (SEARCH-AF)

Screening Education And Recognition in Community pHarmacies of Atrial Fibrillation for stroke prevention (SEARCH-AF): using pulse check and handheld ECG to identify atrial fibrillation in an ambulatory population aged 65 years and over

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000406808
Acronym
SEARCH-AF
Enrollment
1000
Registered
2012-04-11
Start date
2012-06-02
Completion date
2013-01-25
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Atrial fibrillation (AF) is the most common heart arrhythmia affecting at least 240,000 Australians. Prevalence rises with age from approximately 1% of the whole population to 5% in those over 65 years. People with AF are up to seven times more likely to have a stroke than the general population, and AF related strokes are also likely to be more severe. In addition, one in every six strokes is AF related. Stroke is highly preventable in AF with the use of appropriate thromboprophylaxis. Therefore early identification and appropriate evidence based management of AF could lead to subsequent stroke prevention, significant reduction in the overall stroke burden and substantial savings to the health system. Our hypothesis is that a simple community pharmacy based screening program may be effective in detecting those with undiagnosed AF. The specific aims are to: 1. To identify the number of newly identified AF in people aged 65 years and over in a pharmacy setting. 2. Determine the feasibility of screening for AF using a pulse check and handheld singlelead electrocardiography (ECG) device in people aged 65 years and over. 3. Inform refinement of the intervention through the use of process measures with view to establishing a larger crosssectional study. 4. To increase the skills and knowledge of pharmacists regarding atrial fibrillation screening and management. We propose a crosssectional study offered in 10 community pharmacies in the districts surrounding the Concord Hospital. People aged 65 and over, attending community pharmacies will be invited to volunteer for the screening. The screening will consist of a pulse check, brief medical history including pharmacotherapy and screen of AF symptoms and an assessment with a handheld singlelead ECG device. The pharmacist will communicate the provisional diagnosis to the participants treating general practitioner (GP). For those participants suspected of having AF, the research team will contact the both the participant and their GP. We will invite the GP to refer their patient to Concord Hospital cardiology clinic for definitive diagnosis and standard cardiology care as appropriate. The primary outcome measure will be the number of newly identified atrial fibrillation in a community cohort aged 65 years and over. A process evaluation will also be undertaken to better appreciate factors that might influence sustainability beyond the trial setting.

Interventions

Community pharmacists will screen members of the general public for atrial fibrillation using a combination of a manual pulse check and a handheld single-lead ECG (using the AliveCor Heart Monitor for iPhone). This will be a once off screening of approximately 5-10 minutes duration. Following the screening, the pharmacist will contact the participants GP via letter, stating the provisional diagnosis. A cardiologist will review all of the single-lead ECG recordings to ensure the pharmacists inter

Community pharmacists will screen members of the general public for atrial fibrillation using a combination of a manual pulse check and a handheld single-lead ECG (using the AliveCor Heart Monitor for iPhone). This will be a once off screening of approximately 5-10 minutes duration. Following the screening, the pharmacist will contact the participants GP via letter, stating the provisional diagnosis. A cardiologist will review all of the single-lead ECG recordings to ensure the pharmacists interpretation is correct. The GP will be further contacted by the research team if the diagnosis is other than reported by the pharmacist. The screening trial will be conducted over a 6 month period.

Sponsors

Concord General Repatriation Hospital
Lead SponsorHospital

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
65 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

People will be eligible to participate if they are aged 65 years or over.

Exclusion criteria

Exclusion criteria include diagnosis of a severe coexisting medical condition that would prevent participation (eg, dementia, terminal illness).

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 26, 2026