None listed
Conditions
Brief summary
Overweight and obesity is a major health problem increasing the risk of several lifestyle diseases including type 2 diabetes, cardiovascular disease and certain forms of cancers and effective strategies for weight loss are needed. A number of studies have shown equal effect on weight loss when using intermittent fasting (fasting 24h followed by 24h ad libitum eating) vs. continuous dieting. Preliminary data has suggested that an intermittent diet strategy using an energy restricted diet, in line with the continuous diet, instead of fasting produces greater weight loss compared to continuous dieting; but this has been investigated only in men. This research will look into the effect of intermittent dieting vs. continuous dieting in a cohort of overweight and obese women Aim: To investigate the effect on weight loss of an intermittent energy restriction compared to a continuous energy restriction, in healthy overweight to obese participants. Hypothesis: An intermittent energy restriction will result in greater weight loss.
Interventions
Volunteers will be assigned to one of two groups for an 8-week study. One group will diet continuously while the other will diet intermittently: 1 week dieting with an energy intake of no more than 5.5Mj, 1 week not dieting (no energy restriction), throughout the 8 weeks. Instruction in how to achieve the energy level of 5.5 MJ will be given at the beginning of the study and dietary advise will be given at every other week for 8 weeks. The continuous dieting group will be instructed in how to
Volunteers will be assigned to one of two groups for an 8-week study. One group will diet continuously while the other will diet intermittently: 1 week dieting with an energy intake of no more than 5.5Mj, 1 week not dieting (no energy restriction), throughout the 8 weeks. Instruction in how to achieve the energy level of 5.5 MJ will be given at the beginning of the study and dietary advise will be given at every other week for 8 weeks. The continuous dieting group will be instructed in how to achieve the 5.5MJ and reinforcement will be given at fortnightly visits for 8 weeks. A food frequency questionnaire will be completed and dietary education will be delivered in a group session at UniSA at the beginning of the study and each volunteer will be weighed and measured privately every two weeks. The first visit will take approximately an hour; follow up visits will be shorter. A 1-year follow up visit will also be held to assess the long term effect.
Sponsors
University of South Australia
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
Women over age 18 Body mass index (BMI) >27 kg/m2 No concomitant serious illness
Exclusion criteria
Exclusion: Previous surgery for weight reduction Pregnant or breast feeding women Alcohol intake in excess of 5 standard drinks per day Participation in other ongoing trials aiming at altering energy or macronutrient intake
Outcome results
None listed