None listed
Conditions
Brief summary
Post-prandial lipemia is an elevation in triglyceride (TG) and chylomicron remnants that occurs after digesting a fat-containing meal. Post-prandial lipemia has been established as a risk factor for atherosclerosis and cardiovascular disease. However, dietary intake of green tea and aerobic exercise results in lowered post-prandial lipemia. The study will examine the effect of a different form of exercise called high intensity intermittent exercise (HIIE) and green tea on postprandial lipemia.
Interventions
Each subject will be involved with four arms of the trial which will consist of: a placebo, a green tea capsule, an exercise bout, and a green tea capsule and exercise bout condition. The green tea and placebo capsules will be ingested with lunch and dinner on the day before the high fat meal and in the morning, 1.5 hour before the high fat meal. The high fat meal will be consumed after overnight fasting early in the morning. exercise will be performed 12 hours before consumption of the high f
Each subject will be involved with four arms of the trial which will consist of: a placebo, a green tea capsule, an exercise bout, and a green tea capsule and exercise bout condition. The green tea and placebo capsules will be ingested with lunch and dinner on the day before the high fat meal and in the morning, 1.5 hour before the high fat meal. The high fat meal will be consumed after overnight fasting early in the morning. exercise will be performed 12 hours before consumption of the high fat meal. The green tea will consist of a standardized green tea (total of 340 mg polyphenols and 136 mg EGCG), maltodextrin, microcrystalline cellulose, sodium croscarmellose, stearic acid, silicon dioxide, magnesium stearate (vegetable origin), hydroxypropylmethyl cellulose coating, and glycerine (vegetable origin). The amount of green tea contained in each capsule will be equivalent to three cups of green tea. Exercise will consist of cycling on a stationary bike for 20 minutes. The high fat meal will be in milkshake form and will consist of 270 ml of whipping cream and 65 g of specialty ice cream. The meal will provide 4.1 MJ (980 kcal; 0.05 MJ/kg body weight), 100 g fat (1.1 g/kg); 66.5 g saturated, 29.5 monounsaturated, 4.0 g polyunsaturated, 17 g carbohydrate (0.2 g/kg), and 3 g protein (0.03 g/kg). Percent fat is about 92%. This meal has been successfully used in previous studies to induce postprandial lipemia. Twelve hours before the high fat meal subjects will perform 20 minutes of high intensity intermittent exercise when in the exerclse alone or exercise/green tea condition. Exercise will consist of cycling flat out for 8 s then resting (turn the pedals over slowly) for 12 s continuously for a 20-min period. Thus, in a 20-min period subjects will cycle vigorously for 8 min and cycle slowly for 12 min (60 sprints). Load will be determined from subject’s maximal oxygen uptake values. Heart rates are typically between 150 and 160 bpm during this protocol. Period between conditions will be one week. One order out of a possible six different order of the above conditions will be randomly assigned to subjects'
Sponsors
University New South wales
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
Male
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
Male, aged between 18 and 30 years. No history of exercise or consumption of green tea. exercise history will be assessed by a lifestyle questionnaire and use of the seven day physical activity recall questionnaire. Exclusion will be based on an exercise regimen that involves moderately hard exercise for more than two times per week.
Exclusion criteria
Exclusion - Smokers - On any regular medication - Regular green tea consumption - Suffering from diabetes or any cardiovascular diseases - Any other clinical conditions which may prevent them from participating in this clinical trial
Outcome results
None listed