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Under-Recognition of Allergic conjunctivitis in Patients with Allergic Rhinitis

The Effect of Olopatadine Hydrochloride on total ocular symptoms score in Non-allergic conjunctivitis/rhinitis individuals.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000143820
Enrollment
20
Registered
2012-02-01
Start date
2012-02-13
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Aim: To determine the most effective way of detecting the incidence of allergic conjunctivitis (AC). Method: The first step includes asking patients in an allergy specialist's outpatient clinic about their Total Ocular Symptom Score (tearing, itching and eye redness), then asking them about indirect symptoms of AC (squinting, blinking, frontal headaches or eyelid dermatitis), and finally using an olopatadine challenge to determine if any chronic, undetected symptoms of AC are relieved and thus suffered. A control group will be used to determine if the lubricating effects of the olopatadine eye drops is acting as the relieving factor in the intervention group.

Interventions

Participants will be asked about their indirect symptoms of AC (squinting, blinking, frontal headaches or eyelid dermatitis) to assess whether they suffer. Then total Ocular Symptom Score (TOSS) (tearing, itching and eye redness) will be assessed. Then, one drop of olopatadine hydrochloride to each eye, ONCE ONLY. Then 5 minutes will pass before assessing TOSS again.

Sponsors

A/Prof Peter Smith
Lead SponsorIndividual

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

No allergic conjunctivitis Over 18 years Not pregnant CONFIRMED PARTICIPANTS CANT HAVE AR/AC

Exclusion criteria

allergic conjunctivitis/rhinitis

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026