Changes in bone structure, lean mass, and glucose metabolism after stroke: a prospective study

Changes in bone structure, lean mass, and glucose metabolism in people with stroke: a two year observation study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12612000123842

Enrollment

Registered

2012-01-25

Start date

2010-06-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study is observing changes which occur to bone density and structure, muscle mass, and glucose metabolism (the way that the body converts sugars to energy), after stroke. We are investigating how these outcomes are influenced by physical activity after stroke. This information will be used in future designs of rehabilitation programs aimed at improving stroke patients' health and recovery.

Interventions

This is a two year longitudinal, observation study of changes to bone density and structure, body composition and glucose metabolism after stroke

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

The inclusion criteria are (1) a diagnosis of hemispheric stroke , (2) onset of stroke <1 week, (3) medically stable, (4) unable to ambulate within the first week after stroke, (5) able to understand simple verbal commands.

Exclusion criteria

(1) brainstem or cerebellar stroke, (2) previous stroke in addition to the current admission, (3) known type 1 or type 2 diabetes (4) neurological conditions other than stroke (e.g. Parkinson’s disease) (5) significant musculoskeletal condition impacting on function (e.g. amputation, severe arthritis), (6) current or recent use of bone resorption inhibitors

Outcome results