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How to distinguish an active air leak from a pleural space effect by means of a digital chest drain system

Differences between active air leak and pleural space effect detected by means a digital chest drain system on patients submitted to lung resections and plural biopsies

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12612000108819
Acronym
DBAALPSE
Enrollment
125
Registered
2012-01-23
Start date
2010-03-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Bachground: In this prospective study we aimed to recognize a pleural space effect, distinguishing it from an active air leak, by means of a digital chest drain system providing a continuous air flow and pleural pressures check. Methods: Since March 2010 to October 2011, we employed 144 digital drains for 125 patients undergone 138 thoracic surgical procedures. Results: We observed: 18 active air leaks (12.5%), among which 4 prolonged (2.8%), all characterized by high differential pleural pressure, especially due to an increased mean expiratory pressure (>1 cmH2O) (p <0.0001), and significantly related to upper lobe resections (p: 0.00017), a chest tube removal time later than the fifth post-operative day (p <0.0001), an increasing pneumothorax after a one day provocative clamping (p <0.0001); three late air leaks (2.1%), all long lasting (p <0.0001), predicted by pressure curves divergency before the air flow appearance. Moreover, we reported 25 pleural space effects (17.4%), equally characterized by a high differential pleural pressure, but mainly due to a lower mean inspiratory pressure (<20 cmH2O) (p <0.0001), and especially related to surgical pleurodesis procedures (p: 0.0003) and wide lung resections (p: 0.0002); none of these patients had an increasing pneumothorax after provocative clamping. Conclusions: A digital chest drain system ensuring a continuous air flow and pleural pressures measurement could clearly identify a pleural space effect, avoiding the frequent misinterpretation with an active air leak and allowing to safely remove a chest tube at the right time.

Interventions

In this observational study we aimed to recognize a pleural space effect, distinguishing it from an active air leak, by means of a digital chest drain system providing a continuous air flow and pleural pressures check. Since March 2010 to October 2011, we employed 144 digital drains for 125 patients undergone 138 thoracic surgical procedures. We observed: 18 active air leaks (12.5%), among which 4 prolonged (2.8%), all characterized by high differential pleural pressure, especially due to an in

In this observational study we aimed to recognize a pleural space effect, distinguishing it from an active air leak, by means of a digital chest drain system providing a continuous air flow and pleural pressures check. Since March 2010 to October 2011, we employed 144 digital drains for 125 patients undergone 138 thoracic surgical procedures. We observed: 18 active air leaks (12.5%), among which 4 prolonged (2.8%), all characterized by high differential pleural pressure, especially due to an increased mean expiratory pressure (>1 cmH2O) (p <0.0001), and significantly related to upper lobe resections (p: 0.00017), a chest tube removal time later than the fifth post-operative day (p <0.0001), an increasing pneumothorax after a one day provocative clamping (p <0.0001); three late air leaks (2.1%), all long lasting (p <0.0001), predicted by pressure curves divergency before the air flow appearance. Moreover, we reported 25 pleural space effects (17.4%), equally characterized by a high differential pleural pressure, but mainly due to a lower mean inspiratory pressure (<20 cmH2O) (p <0.0001), and especially related to surgical pleurodesis procedures (p: 0.0003) and wide lung resections (p: 0.0002); none of these patients had an increasing pneumothorax after provocative clamping. A digital chest drain system ensuring a continuous air flow and pleural pressures measurement could clearly identify a pleural space effect, avoiding the frequent misinterpretation with an active air leak and allowing to safely remove a chest tube at the right time.

Sponsors

I.R.C.C.S. - C.R.O.B. Basilicata Regional Cancer Institute
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to 88 Years
Healthy volunteers
No

Inclusion criteria

Patients submitted to thoracic surgery interventions

Exclusion criteria

Severe lung emphysema - re-do-surgery - no touch lung surgery

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026