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Aboriginal Cord Delayed Clamping Study: investigating delayed cord clamping versus immediate cord clamping for term newborn Aboriginal infants from remote Aboriginal communities.

Effect of delayed cord clamping on the haemoglobin levels of term newborn Aboriginal infants from remote Aboriginal communities: a pilot randomized controlled trial.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12612000071820
Acronym
ACDC
Enrollment
72
Registered
2012-01-16
Start date
2012-01-19
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Anaemia is prevalent among Aboriginal infants under 12 months old. Delayed cord clamping is a simple way to provide extra blood to the newborn baby. Strong evidence from randomized controlled trials has shown its benefits for neonatal health and reducing anaemia in early infancy. The beneficial effects on Aboriginal infants and beyond the first 6 months of life are still unknown. It is clinically important to determine if this simple intervention at birth will impact greatly the health of remote Aboriginal infants with high risk of anaemia due to poor access to nutrition later in infancy. This RCT will enroll 72 Aboriginal pregnant women from remote aboriginal communities who will give birth at 36-42 weeks gestation by uncomplicated NVD or CS. They will be randomly assigned to either receive the interventional delayed cord clamping until the cord stops pulsating or up to 3 minutes with baby held below level of placenta or vaginal introitus or the standard care immediate cord clamping soon after birth under 1 minute. The primary research question is whether haemoglobin level at discharge is greatest in babies after delayed cord clamping.

Interventions

Delayed cord clamping until the cord stops pulsating (at least 1 minute and no more than 3 minutes after delivery) with baby held below level of placenta or vaginal introitus. If there are complications that arise with the delivery or the baby is in distress at birth, immediate cord clamping is done to allow for neonatal resuscitation.

Sponsors

Menzies School of Health Research
Lead SponsorOther Collaborative groups

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

pregnant Aboriginal women usually resident in a remote Aboriginal community at 36 to 42 weeks gestation who are expected to give birth by uncomplicated normal vaginal delivery or elective Caesarian section.

Exclusion criteria

pregnancies complicated by maternal hypertension, pre-eclampsia, risk of post-partum haemorrhage, evidence of intra-uterine growth restriction (estimated fetal weight <10th centile) or congenital malformations

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026