None listed
Conditions
Brief summary
The objective is to investigate whether there are differences between insomnia sufferers who have a specific type of insomnia (hyperarousal insomnia) and those who suffer from general insomnia but do not have elements of hyperarousal. As a result, this study will use a brain imaging technique called Magnetic resonance spectroscopy (MRS) in order to attempt to find differences in brain neurochemistry between these two different types of insomnia sufferers.
Interventions
Magnetic Resonance Spectroscopy (MRS) brain imaging will be used in this study. This involves an hour long brain imaging scan that will be used to examine brain neurochemistry within insomnia sufferers. The overall experiment will take three hours to complete.
Participants will be grouped according to responses provided on the hyperarousal questionnaire - with those high on this scale being included in the insomnia with hyperarousal group. A control group will also be determined by this scale.
Magnetic Resonance Spectroscopy (MRS) brain imaging will be used in this study. This involves an hour long brain imaging scan that will be used to examine brain neurochemistry within insomnia sufferers. The overall experiment will take three hours to complete. Participants will be grouped according to responses provided on the hyperarousal questionnaire - with those high on this scale being included in the insomnia with hyperarousal group. A control group will also be determined by this scale. Those who have insomnia but a low score on the hyperarousal scale will be included as controls.
Sponsors
University of Sydney
Eligibility
Sex/Gender
All
Age
23 Years to 56 Years
Healthy volunteers
Yes
Inclusion criteria
1. Symptoms of Insomnia Disorder as diagnosed by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria for insomnia disorder (APA, 2013) specifically: Difficulty initiating or maintaining sleep or waking up too early for at least 3 nights per week, for at least 3 months, with adequate opportunity and circumstances for sleep 2. Stable sleep/wake schedule with no shift work 3. Able to give informed, written consent 4. Fluent speaker of English 5. Referred by a sleep physician to have a routine sleep study as part of Medicare
Exclusion criteria
1. Pregnancy or lactation 2. Active illicit substance use or alcohol/caffeine dependence 3. Medications that interfere with sleep (within 1 month of assessment) 4. Psychiatric disorders, other than mild to moderate depression (on the Depression Anxiety Stress Scales) 5. Another sleep disorder evaluated by a Sleep Physician / Sleep Psychologist that better explains the complaint of sleep loss. 6. Severe cognitive impairment that does not allow patients to consent or follow study instructions 7. Overnight shift workers and recent time-zone travel (within last 2 months) 8. Actively treated sleep disorder (e.g. CPAP/CBT-I)
Outcome results
None listed